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  8. Nafamostat mesylate, Tocris Bioscience™

Nafamostat mesylate, Tocris Bioscience™

Catalog No. 308150
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

Serine protease inhibitor, inhibits tryptase

Nafamostat mesylate is a broad spectrum serine protease inhibitor. Displays selectivity for human tryptase when used at relatively low concentrations. Reduces eosinophil infiltration, mast cell activation and airway responsiveness in a murine model of asthma. Inhibits SARS-CoV-2 infection in vitro (EC50 = 22.50 μM).

Tocris products are for biomedical research use only. They are not intended for human or veterinary use.

Chemical Identifiers

CAS 82956-11-4
Molecular Formula C21H25N5O8S2
Molecular Weight (g/mol) 539.58
MDL Number MFCD00941430
InChI Key SRXKIZXIRHMPFW-UHFFFAOYSA-N
Synonym nafamostat mesylate, futhan, nafamostat mesilate, nafamstat mesilate, 6-amidino-2-naphthyl 4-guanidino-benzoate dimethanesulphonate, 6-amidino-2-naphthyl-4-guanidinobenzoate dimethanesulfonate, nafamostat mesylate fut-175, nafamstatmesilate, ronastat tn
PubChem CID 5311180
IUPAC Name amino({[4-({[6-(azaniumylmethanimidoyl)naphthalen-2-yl]oxy}carbonyl)phenyl]imino})methanaminium dimethanesulfonate
SMILES CS([O-])(=O)=O.CS([O-])(=O)=O.NC([NH3+])=NC1=CC=C(C=C1)C(=O)OC1=CC=C2C=C(C=CC2=C1)C([NH3+])=N

Specifications

Quantity 50 mg
Formula Weight 539.59
Percent Purity >99%
Chemical Name or Material Nafamostat mesylate

Safety and Handling

Recommended Storage Desiccate at +4°C
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