N,N-Dimethylacetamide, 99%, Thermo Scientific Chemicals

Description

N,N-Dimethylacetamide is used as a polar solvent in organic synthesis as well as in reactions involving strong bases such as sodium hydroxide. It is also used as a solvent for fibers like polyacrylonitrile, spandex, as an excipient in drugs viz. vumon, busulfex and in the adhesive industry. It finds application as a reaction medium in the production of pharmaceuticals, agrochemicals, dyes and plasticizers. It is widely used in polymer industry due to its high solving power for high molecular-weight polymers and synthetic resins. It plays an important role as a catalyst in various reactions viz. cyclization, halogenation, cynidation, alkylation and dehydrogenation and increases the yield of main products. It is also used as an extracting agent for oil and gases, in paint removers, in the production of photo-resist stripping compounds and as booster solvent in coatings.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
N,N-Dimethylacetamide is used as a polar solvent in organic synthesis as well as in reactions involving strong bases such as sodium hydroxide. It is also used as a solvent for fibers like polyacrylonitrile, spandex, as an excipient in drugs viz. vumon, busulfex and in the adhesive industry. It finds application as a reaction medium in the production of pharmaceuticals, agrochemicals, dyes and plasticizers. It is widely used in polymer industry due to its high solving power for high molecular-weight polymers and synthetic resins. It plays an important role as a catalyst in various reactions viz. cyclization, halogenation, cynidation, alkylation and dehydrogenation and increases the yield of main products. It is also used as an extracting agent for oil and gases, in paint removers, in the production of photo-resist stripping compounds and as booster solvent in coatings.

Solubility
Miscible with water, benzene, alcohol, acetone, ether, esters and ketones.

Notes
Hygroscopic. Incompatible with strong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 127-19-5
• Molecular Formula: C4H9NO
• Molecular Weight (g/mol): 87.12
• MDL Number: MFCD00008686
• InChI Key: FXHOOIRPVKKKFG-UHFFFAOYSA-N
• Synonym: dimethylacetamide, dmac, acetamide, n,n-dimethyl, acetdimethylamide, dimethyl acetamide, n,n-dimethyl acetamide, dimethylamide acetate, n,n-dimethylethanamide, dimethylacetone amide, acetyldimethylamine
• PubChem CID: 31374
• ChEBI: CHEBI:84254
• IUPAC Name: N,N-dimethylacetamide
• SMILES: CN(C)C(C)=O

• Melting Point: -20°C
• Density: 0.94
• Boiling Point: 165°C to 166°C
• Flash Point: 70°C (158°F)
• Odor: Ammonia-like
• Refractive Index: 1.4385
• Linear Formula: CH₃CON(CH₃)₂
• Quantity: 500 mL
• Beilstein: 1737614
• Merck Index: 14,3227
• Solubility Information: Miscible with water,benzene,alcohol,acetone,ether,esters and ketones.
• Formula Weight: 87.12
• Percent Purity: 99%
• Chemical Name or Material: N,N-Dimethylacetamide

Safety and Handling

Hazard Category	H227-H312+H332-H360D
Hazard Statement	GHS H Statement H360-H312-H332-H227 May damage fertility or the unborn child. Harmful in contact with skin. Harmful if inhaled. Combustible liquid.
Precautionary Statement	P201-P202-P210-P261-P271-P281-P302+P352-P304+P340-P308+P313-P312-P363-P370+P378q-P501c
DOTInformation	Hazard Class: 6.1; Packaging Group: III
EINECSNumber	204-826-4
RTECSNumber	AB7700000
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only