N-Methyl-N-(trimethylsilyl)trifluoroacetamide, 97%, Thermo Scientific Chemicals

Description

N-Methyl-N-(trimethylsilyl)trifluoroacetamide is used as a silylating reagent that forms volatile derivatives for GC-MS analysis. It acts as a pharmaceutical intermediate and metabolite of Famprofazone in humans. It is also used in the detection of steroid hormones 17-alfa-ethynylestradiol and estrone.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
N-Methyl-N-(trimethylsilyl)trifluoroacetamide is used as a silylating reagent that forms volatile derivatives for GC-MS analysis. It acts as a pharmaceutical intermediate and metabolite of Famprofazone in humans. It is also used in the detection of steroid hormones 17-alfa-ethynylestradiol and estrone.

Solubility
Immiscible with water.

Notes
Moisture sensitive. Store in a cool place. Incompatible with strong oxidizing agents and strong acids.

Specifications

Chemical Identifiers

• CAS: 24589-78-4
• Molecular Formula: C6H12F3NOSi
• Molecular Weight (g/mol): 199.25
• MDL Number: MFCD00000411
• InChI Key: MSPCIZMDDUQPGJ-UHFFFAOYSA-N
• Synonym: mstfa, n-methyl-n-trimethylsilyl trifluoroacetamide, 2,2,2-trifluoro-n-methyl-n-trimethylsilyl acetamide, n-methyl-n-trimethylsilyltrifluoroacetamide, acetamide, 2,2,2-trifluoro-n-methyl-n-trimethylsilyl, n-methyl-n-trimethylsilyl-trifluoroacetamide, acmc-209tfm
• PubChem CID: 32510
• ChEBI: CHEBI:85064
• IUPAC Name: 2,2,2-trifluoro-N-methyl-N-trimethylsilylacetamide
• SMILES: CN(C(=O)C(F)(F)F)[Si](C)(C)C

• Density: 1.076
• Boiling Point: 130°C to 132°C
• Flash Point: 25°C (77°F)
• Refractive Index: 1.38
• Quantity: 100 g
• UN Number: UN1993
• Beilstein: 1941550
• Sensitivity: Moisture sensitive
• Solubility Information: Immiscible with water.
• Formula Weight: 199.25
• Percent Purity: 97%
• Chemical Name or Material: N-Methyl-N-(trimethylsilyl)trifluoroacetamide

Safety and Handling

Hazard Category	H226-H315-H319-H335
Hazard Statement	GHS H Statement H226-H315-H319-H335 Flammable liquid and vapour. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P210-P233-P235-P240-P241-P242-P243-P261-P264b-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P312-P332+P313-P363-P370+P378q-P501c
DOTInformation	Transport Hazard Class: 3; Packing Group: III; Proper Shipping Name: FLAMMABLE LIQUIDS, N.O.S.
EINECSNumber	246-331-6
RTECSNumber	AC9800000
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only