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Enzo Life Sciences Myriocin (5 mg) CAS: 35891-70-4
SDP

Supplier:  Enzo Life Sciences BMLSL2260005

Encompass_Preferred

Palmitoyltransferase inhibitor. Potent immunosuppressant ~10 to 100-fold more potent than cyclosporin A (Prod. No. BML-A195). Blocks sphingolipid biosynthesis by inhibiting serine palmitoyltransferase (Ki=0.28nM), therefore useful as a tool to deplete cells of sphingolipids. Induces apoptosis by depletion of cellular sphingolipids. Inhibits proliferation of an IL-2-dependent mouse cytotoxic cell line CTLL-1 (IC50=15nM). Synonyms: ISP-1, Thermozymocidin, 2S,3R,4R,6E-2-Amino-3,4-dihydroxy-2-hydroxymethyl-14-oxo-6-eicosenoic acid. Formula: C21H39NO6. MW: 401.5.

Catalog No. 50-210-0550


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