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Invitrogen™ Guanosine 5'-O-(3-Thiotriphosphate), BODIPY™ FL Thioester, Sodium Salt (BODIPY™ FL GTP-γ-S, Thioester)
Fluorescence may be recovered on binding to G-proteins
Supplier: Invitrogen™ G22183
Description
BODIPY FL GTP-γ-S binds to GTP-binding proteins. To create this fluorescent nucleotide, the BODIPY FL fluorophore was linked through the γ-thiol of GTP-γ-S. The fluorescence of BODIPY FL GTP-γ-S is quenched approx. 90% relative to that of the free dye, but may be recovered on binding to G-proteins. In addition to its potential use for binding studies, the BODIPY FL GTP-γ-S thioether is an important new substrate for Fhit, a member of the histidine triad superfamily of nucleotide-binding proteins.
Drug Discovery and Development, Enzyme and Protein Activity Assays, Phosphatase Activity, Phosphatase Biology, Proteins, Expression, Isolation and Analysis, Target and Lead Identification and Validation
Order Info
Shipping Condition: Wet ice
Specifications
| Guanosine 5'-O | |
| Chemical Labeling, Direct Labeling | |
| 5 mM | |
| 50 μL |
| Store in freezer -5°C to -30°C and protect from light. | |
| Wet Ice | |
| BODIPY™ FL | |
| BODIPY™ |
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Product Title
For Research Use Only. Not for use in diagnostic procedures.
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