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  7. MNI 137, Tocris Bioscience™

MNI 137, Tocris Bioscience™

Catalog No. 438850
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Selective negative allosteric modulator of group II mGlu receptors

Selective negative allosteric modulator of group II mGlu receptors (IC50 values are 8.3 and 12.6 nM for human and rat mGlu2 inhibition of glutamate-induced calcium mobilization). Displays no activity at mGlu1, mGlu4, mGlu5 or mGlu8 receptors in a calcium mobilization assay.

Chemical Identifiers

CAS 946619-21-2
Molecular Formula C15H9BrN4O
Molecular Weight (g/mol) 341.168
InChI Key KMKZCMKOSAKVGY-UHFFFAOYSA-N
Synonym 4-8-bromo-2,3-dihydro-2-oxo-1h-1,5-benzodiazepin-4-yl-2-pyridinecarbonitrile
PubChem CID 25210562
IUPAC Name 4-(8-bromo-2-oxo-1,3-dihydro-1,5-benzodiazepin-4-yl)pyridine-2-carbonitrile
SMILES C1C(=NC2=C(C=C(C=C2)Br)NC1=O)C3=CC(=NC=C3)C#N

Specifications

Quantity 50 mg
Formula Weight 341.16
Percent Purity >98%
Chemical Name or Material MNI 137

Safety and Handling

Recommended Storage Store at +4°C
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