MMP1 Monoclonal Antibody (F15 P3 B6), Invitrogen™

Mouse Monoclonal Antibody

Supplier:  Thermo Scientific MA1771

Catalog No. 01-674-560

Description

MA1-771 contains 100 μg of in vitro produced, protein A purified antibody (1 mg/mL) in PBS containing 1 mg/mL BSA and 0.05% sodium azide. MA1-771 detects MMP-1 from human samples. MA1-771 has been successfully used in Western blot applications. By Western blot, MA1-771 detects a ∽50 kDa band representing MMP-1 from A431 and K562 cell lysates. The MA1-771 immunogen is a synthetic peptide corresponding to residues C(366) S S F G F P R T V K H(376) of human MMP-1.

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants.

Specifications

• Antigen: MMP1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1mg/mL BSA and 0.05% sodium azide
• Gene Accession No.: P03956
• Gene Symbols: MMP1
• Immunogen: Synthetic peptide corresponding to residues C(366) S S F G F P R T V K H(376) of human MMP-1.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: F15 P3 B6
• Conjugate: Unconjugated
• Gene: MMP1
• Gene Alias: 22 kDa interstitial collagenase; 27 kDa interstitial collagenase; CLG; CLGN; Collagenase; collagenase-like A; fibroblast collagenase; Interstitial collagenase; interstitial collagenase A; matrix metallo protease; matrix metallopeptidase 1; matrix metallopeptidase 1 (interstitial collagenase); matrix metallopeptidase 1a; matrix metallopeptidase 1a (interstitial collagenase); matrix metalloprotease 1; matrix metalloproteinase 1; matrix metalloproteinase 1a (interstitial collagenase); Matrix metalloproteinase1; Matrix metalloproteinase-1; Matrix metalloproteinase-1a; McolA; Mcol-A; MMP; MMP1; MMP-1; Mmp1a; MMP-1a; MMPs
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 4312
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid