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  8. ML 281, Tocris Bioscience™

ML 281, Tocris Bioscience™

Catalog No. 488050
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

STK33 inhibitor

Inhibitor of the serine/threonine kinase STK33 (IC50 = 14 nM). Exhibits >700-fold selectivity for STK33 over the structurally related protein kinase A (PKA); also exhibits 550-fold selectivity over Aurora kinase B.

Chemical Identifiers

CAS 1404437-62-2
Molecular Formula C22H19N3O2S
Molecular Weight (g/mol) 389.473
InChI Key HWOYIOLMBQSTQS-UHFFFAOYSA-N
Synonym bg-stk33-59, n-2-3,4-dihydro-3-oxo-2-quinoxalinyl-4-1-methylethyl phenyl-2-thiophenecarboxamide, n-2-3-oxo-3,4-dihydroquinoxalin-2-yl-4-propan-2-yl phenyl thiophene-2-carboxamide
PubChem CID 53377448
IUPAC Name N-[2-(3-oxo-4H-quinoxalin-2-yl)-4-propan-2-ylphenyl]thiophene-2-carboxamide
SMILES CC(C)C1=CC(=C(C=C1)NC(=O)C2=CC=CS2)C3=NC4=CC=CC=C4NC3=O

Specifications

Quantity 50 mg
Formula Weight 389.47
Percent Purity >98%
Chemical Name or Material ML 281

Safety and Handling

Recommended Storage Store at +4°C
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