Maleic acid, 98+%, Thermo Scientific Chemicals

Description

Maleic acid is used as a precursor to fumaric acid, dimethyl maleate and glyoxalic acid. It is an electrophile and acts as dienophine in Diels-Alder reactions. It reacts with drugs to form more stable addition salts like indacaterol maleate, carfenazine, chlorpheniramine, pyrilamine, methylergonovine and thiethylperazine. Its maleate ion is useful in biochemistry as an inhibitor of transaminase reactions.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Maleic acid is used as a precursor to fumaric acid, dimethyl maleate and glyoxalic acid. It is an electrophile and acts as dienophine in Diels-Alder reactions. It reacts with drugs to form more stable addition salts like indacaterol maleate, carfenazine, chlorpheniramine, pyrilamine, methylergonovine and thiethylperazine. Its maleate ion is useful in biochemistry as an inhibitor of transaminase reactions.

Solubility
Soluble in water, acetone, glacial acetic acid, alcohol and concentrated sulfuric acid. Slightly soluble in diethyl ether. Insoluble in benzene and chloroform.

Notes
Incompatible with oxidizing agents, bases, reducing agents, metals and alkalis.

Specifications

Chemical Identifiers

• CAS: 110-16-7
• Molecular Formula: C4H4O4
• Molecular Weight (g/mol): 116.07
• MDL Number: MFCD00063177
• InChI Key: VZCYOOQTPOCHFL-OWOJBTEDSA-N
• Synonym: maleic acid, cis-butenedioic acid, toxilic acid, maleinic acid, malenic acid, 2z-but-2-enedioic acid, 2-butenedioic acid z, maleate, cis-1,2-ethylenedicarboxylic acid, z-butenedioic acid
• PubChem CID: 444266
• ChEBI: CHEBI:18300
• IUPAC Name: (Z)-but-2-enedioic acid
• SMILES: OC(=O)\C=C\C(O)=O

• Melting Point: 132°C to 136°C
• Beilstein: 605762
• Merck Index: 14,5703
• Solubility Information: Soluble in water,acetone,glacial acetic acid,alcohol and concentrated sulfuric acid. Slightly soluble in diethyl ether. Insoluble in benzene and chloroform.
• Formula Weight: 116.07
• Percent Purity: ≥98%
• Density: 1.59
• Quantity: 250 g
• Flash Point: 127°C (260°F)
• Chemical Name or Material: Maleic acid

Safety and Handling

Hazard Category	H302+H312-H314-H317-H335
Hazard Statement	GHS H Statement H302-H315-H319-H317-H335 Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause an allergic skin reaction. May cause respiratory irritation.
Precautionary Statement	P260-P264b-P270-P271-P272-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P333+P313-P363-P501c
DOTInformation	Hazard Class: 8; Packaging Group: II
EINECSNumber	203-742-5
RTECSNumber	OM9625000
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only