Invitrogen™ LRRK2 (WT) Recombinant Protein

Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene, which codes for a multi-domain protein kinase, are considered the most common genetic cause of late-onset autosomal-dominant Parkinson's disease.

Supplier:  Invitrogen™ A15199

Catalog No. A15199

Description

This full-length, purified and active wild-type LRRK2 protein may be useful in research to better understand the native protein, unaffected by mutations, as well as to explore the mechanisms underlying Parkinson's disease.

• Increase disease relevance by interrogating a purified and active full-length LRRK2 protein
• Uncover novel compounds or hits specific to the full-length form
• Advance Parkinson's research using the full-length protein and validated assays

Specifications

• Accession Number: NP_940980.3
• Gene ID (Entrez): 120892
• Quantity: 1 mg
• KinaseFamily: LRRK Kinase Family
• Protein Tag: DYKDDDDK
• Expression System: Baculovirus
• Protein Form: Recombinant, Full Length
• Research Category: Neurobiology

• For Use With (Application): Kinase Assay
• Molecular Weight (g/mol): 288 kDa
• Gene Alias: AURA17, DARDARIN, PARK8, RIPK7, ROCO2
• Species: Human
• Content And Storage: Store at -68 to -85°C. Aliquot at first use to avoid multiple freeze-thaws. If properly stored, this product is guaranteed for 6 months from date of purchase.
• Protein Family: Kinases & Inhibitors
• Form: Liquid