Loratadine, 98+%, Thermo Scientific Chemicals

Description

A nonsedating-type histamine H1-receptor antagonist

Loratadine, is used as a peripheral histamine H1 receptor agonist. It is also used as an orally active antiallergic agent. It is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals and Dyestuff.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Loratadine, is used as a peripheral histamine H1 receptor agonist. It is also used as an orally active antiallergic agent. It is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals and Dyestuff.

Solubility
It is soluble in DMSO (50 mg/ml), ethanol (77 mg/ml at 25°C), water (<1mg/mL at 25°C), chloroform, and methanol.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2 - 8°C. Keep away fom strong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 79794-75-5
• Molecular Formula: C22H23ClN2O2
• Molecular Weight (g/mol): 382.888
• MDL Number: MFCD00672869
• InChI Key: JCCNYMKQOSZNPW-UHFFFAOYSA-N
• Synonym: loratadine, claritin, loratidine, alavert, clarityn, lisino, clarityne, loracert, loradex, bonalerg
• PubChem CID: 3957
• IUPAC Name: ethyl 4-(8-chloro-5,6-dihydrobenzo[1,2]cyclohepta[2,4-b]pyridin-11-ylidene)piperidine-1-carboxylate
• SMILES: CCOC(=O)N1CCC(=C2C3=C(CCC4=C2N=CC=C4)C=C(C=C3)Cl)CC1

• Melting Point: 134°C
• Color: White
• Quantity: 500 mg
• Merck Index: 14,5578
• Solubility Information: It is soluble in DMSO (50mg/ml),ethanol (77mg/ml at 25°C),water (<1mg/ml at 25°C),chloroform,and methanol.
• Formula Weight: 382.88
• Percent Purity: ≥98%
• Physical Form: Powder
• Chemical Name or Material: Loratadine

Safety and Handling

RTECSNumber	TM6129200
TSCA	No
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only