L-(+)-Valinol, 97%, Thermo Scientific Chemicals

Description

L-(+)-Valinol reacts with aldehydes and nitriles to form imines and oxazolines, respectively, for asymmetric synthesis. It is also used for preparation of 4-isopropyloxazolidinones, employed in stereocontrolled aldol and alkylation reactions, synthesis of chiral 2-thiazolidinethiones for aldol reactions, asymmetric alkylation of condensation product with keto acids, asymmetric reactions of its amidines and imines and oxidation of N-protected derivative to the aldehyde.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
L-(+)-Valinol reacts with aldehydes and nitriles to form imines and oxazolines, respectively, for asymmetric synthesis. It is also used for preparation of 4-isopropyloxazolidinones, employed in stereocontrolled aldol and alkylation reactions, synthesis of chiral 2-thiazolidinethiones for aldol reactions, asymmetric alkylation of condensation product with keto acids, asymmetric reactions of its amidines and imines and oxidation of N-protected derivative to the aldehyde.

Solubility
Soluble in water.

Notes
Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. Incompatible with oxidizing agents. It is sensitive to air. Store under dry inert gas.

Specifications

Chemical Identifiers

• CAS: 2026-48-4
• Molecular Formula: C5H13NO
• Molecular Weight (g/mol): 103.17
• MDL Number: MFCD00064296
• InChI Key: NWYYWIJOWOLJNR-RXMQYKEDSA-N
• Synonym: l-valinol, s-+-2-amino-3-methyl-1-butanol, 2s-2-amino-3-methylbutan-1-ol, l-+-valinol, h-valinol, s-2-amino-3-methylbutan-1-ol, s-2-amino-3-methyl-1-butanol, 1-butanol, 2-amino-3-methyl-, 2s, s-2-amino-3-methyl-butan-1-ol
• PubChem CID: 640993
• IUPAC Name: (2S)-2-amino-3-methylbutan-1-ol
• SMILES: CC(C)[C@H](N)CO

• Refractive Index: 1.4548
• Density: 0.926
• Boiling Point: 80°C to 81°C (8mmHg)
• Melting Point: 30°C to 35°C
• Quantity: 25 g
• Flash Point: 78°C (172°F)
• Optical Rotation: +17° (c=10 in Ethanol)
• Sensitivity: Air sensitive
• Beilstein: 1719137
• Solubility Information: Soluble in water.
• Formula Weight: 103.17
• Percent Purity: 97%
• Chemical Name or Material: L-(+)-Valinol

Safety and Handling

Hazard Category	H315-H319-H335
Hazard Statement	GHS H Statement H315-H319 Causes skin irritation. Causes serious eye irritation.
Precautionary Statement	P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
EINECSNumber	217-975-5
TSCA	No
Recommended Storage	Keep cold

SDS

RUO – Research Use Only