L-Glutathione, reduced, 98+%, Thermo Scientific Chemicals

Description

A tripeptide used for reductive cleavage of disulfide bonds

A tripeptide used for the reductive cleavage of disulfide bonds L-Glutathione is used in the treatment of lung diseases for patients who are HIV positive. It protects the cancerous cells by conferring resistance to chemotherapeutic drugs. It is involved in many aspects of metabolism including transport of g-glutanyl amino acids and reductive cleavage of disulfide bonds. As an antioxidant, it prevents damage to important cellular components that arise due to reactive oxygen species like free radicals and peroxide. It is also used to decrease the concentrations of inflammatory cytokines (IL-6, IL-18) as well as involved in increasing the level of serum Ca²⁺ ions. It is also used in white wine production.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble in water, dimethyl formamide, ethanol, phosphate buffered saline, diluted alcohol, liquid ammonia and dimethyl sulfoxide.

Notes
Store in cool place. Incompatible with strong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 70-18-8
• Molecular Formula: C10H17N3O6S
• Molecular Weight (g/mol): 307.321
• MDL Number: MFCD00065939
• InChI Key: RWSXRVCMGQZWBV-WDSKDSINSA-N
• Synonym: glutathione, l-glutathione, glutathion, glutathione-sh, glutinal, isethion, tathion, reduced glutathione, deltathione, neuthion
• PubChem CID: 124886
• ChEBI: CHEBI:16856
• IUPAC Name: (2S)-2-amino-5-[[(2R)-1-(carboxymethylamino)-1-oxo-3-sulfanylpropan-2-yl]amino]-5-oxopentanoic acid
• SMILES: C(CC(=O)NC(CS)C(=O)NCC(=O)O)C(C(=O)O)N

• Melting Point: ∽193°C (decomposition)
• Color: White
• Quantity: 5 g
• Beilstein: 1729812
• Merck Index: 14,4475
• Solubility Information: Soluble in water,dimethyl formamide,ethanol,phosphate buffered saline,diluted alcohol,liquid ammonia and dimethyl sulfoxide.
• Optical Rotation: −17° (c=2 in Water)
• Formula Weight: 307.33
• Percent Purity: ≥98%
• Physical Form: Crystalline Powder
• Chemical Name or Material: L-Glutathione, reduced

Safety and Handling

EINECSNumber	200-725-4
RTECSNumber	MC0556000
TSCA	Yes
Recommended Storage	Keep cold

SDS

RUO – Research Use Only