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JZP 361, >99%, Tocris Bioscience™

Potent and selective reversible MAGL inhibitor

Supplier: R&D Systems 5851/50

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Catalog No. 58-515-0

$694.84 / Each of 1

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Description

Potent and selective reversible MAGL inhibitor (IC50 = 46 nM). Exhibits 35-fold and 150-fold higher selectivity over human FAAH and ABHD6, respectively (IC50 values are 1.79 and 7.24 μM, respectively). Displays affinity for H1 receptors (pA2 = 6.81). Exhibits no activity at cannabinoid receptors at 10 μM.

Specifications

Chemical Name or Material	[4-(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinyl](1H-1,2,4-
Purity Grade Notes	>99%
Quantity	50 mg
Formula Weight	405.88

CAS	1680193-80-9
Linear Formula	C₂₂H₂₀ClN₅O
Solubility Information	Soluble to 100mM in DMSO and to 20mM in ethanol

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Safety and Handling

Recommended Storage : Store at 4deg;C

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JZP 361, >99%, Tocris Bioscience™

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