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Gibco™ Human R-Spondin-2 Recombinant Protein, PeproTech®
CHO cells Recombinant Protein
$87.00 - $3240.00
Specifications
| Accession Number | Q6UXX9 |
|---|---|
| For Use With (Application) | Functional Assay |
| Formulation | protein with no preservative |
| Gene ID (Entrez) | 340419 |
| Molecular Weight (g/mol) | 24.4 |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
12043100UG
|
Gibco™
12043100UG |
100 μg |
Each for $648.00
|
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120-43-1MG
|
Gibco™
120431MG |
1 mg |
Each for $3,240.00
|
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|
120-43-20UG
|
Gibco™
1204320UG |
20 μg |
Each for $211.00
|
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|
12043250UG
|
Gibco™
12043250UG |
250 μg |
Each for $1,134.00
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12043500UG
|
Gibco™
12043500UG |
500 μg |
Each for $1,944.00
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120-43-5UG
|
Gibco™
120435UG |
5 μg |
Each for $87.00
|
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Description
The R-Spondin (Rspo) proteins belong to the Rspo family of Wnt modulators. Currently, the family consists of four structurally-related, secreted ligands (Rspo 1-4), all containing furin-like and thrombospondin structural domains. The Rspo proteins can interact with the Frizzled/LRP6 receptor complex in a manner that causes the stabilization, and resulting accumulation, of the intracellular signaling protein, beta-catenin. This activity effectively activates and increases the subsequent nuclear signaling of beta-catenin. R-Spondin can also bind to the previously discovered G-protein coupled receptors, LGR-4 and LGR-5. Rspo/beta-catenin signaling can act as an inducer of the transformed phenotype, and can also regulate the proliferation and differentiation of certain stem cell populations.Specifications
| Q6UXX9 | |
| protein with no preservative | |
| 24.4 | |
| CHO cells | |
| RUO | |
| 2610028F08Rik; AA673245; CRISTIN2; cristin-2; cysteine-rich and single thrombospondin domain-containing protein 2; D430027K22; ftls; hRspo2; mCristin-2; RGD1562331; Roof plate-specific spondin-2; Rspo2; R-spondin 2; R-spondin 2 homolog; R-spondin 2 homolog (Xenopus laevis); R-spondin-2; UNQ9384/PRO34209 | |
| Human | |
| Recombinant | |
| Lyophilized |
| Functional Assay | |
| 340419 | |
| Human R-Spondin-2 | |
| -20°C | |
| <1 EU/μg | |
| RSPO2 | |
| Unconjugated | |
| ASYVSNPICK GCLSCSKDNG CSRCQQKLFF FLRREGMRQY GECLHSCPSG YYGHRAPDMN RCARCRIENC DSCFSKDFCT KCKVGFYLHR GRCFDECPDG FAPLEETMEC VEGCEVGHWS EWGTCSRNNR TCGFKWGLET RTRQIVKKPV KDTILCPTIA ESRRCKMTMR HCPGGKRTPK AKEKRNKKKK RKLIERAQEQ HSVFLATDRA NQ | |
| ≥ 95% by SDS-PAGE gel and HPLC analyses. |
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