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Homoharringtonine, Tocris Bioscience™

Catalog No. 141610
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Quantity:
10 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Inhibitor of protein synthesis; antileukemic agent

Inhibitor of protein synthesis. Blocks elongation phase of translation by binding to the 60-S ribosome subunit. Antileukemic.

Chemical Identifiers

CAS 26833-87-4
Molecular Formula C29H39NO9
Molecular Weight (g/mol) 545.63
MDL Number MFCD05618221
InChI Key HYFHYPWGAURHIV-ZEDNPHJLSA-N
Synonym dsstox_cid_25678, dsstox_rid_81052, dsstox_gsid_45678
PubChem CID 45356872
IUPAC Name (2R,3S,6R)-4-methoxy-16,18-dioxa-10-azapentacyclo[11.7.0.0²,⁶.0⁶,¹⁰.0¹⁵,¹⁹]icosa-1(20),4,13,15(19)-tetraen-3-yl 1-methyl 3-hydroxy-3-(4-hydroxy-4-methylpentyl)butanedioate
SMILES COC(=O)CC(O)(CCCC(C)(C)O)C(=O)O[C@H]1[C@@H]2C3=CC4=C(OCO4)C=C3CCN3CCC[C@]23C=C1OC

Specifications

Quantity 10 mg
Formula Weight 545.63
Percent Purity >99%
Chemical Name or Material Homoharringtonine

Safety and Handling

Recommended Storage Store at Room Temperature
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