Gibco™ HEP10, Pooled Human Cryopreserved Hepatocytes

HEP10, Pooled Human Cryopreserved Hepatocytes

Supplier:  Gibco™ HMCS10

Catalog No. 50-591-338

Description

Get the convenience, affordability, and power of a pooled population of hepatocytes in a single vial. HEP10™ Pooled Human Hepatocytes are a representative population of 10 different donor hepatocytes that have been isolated using our novel patent-pending CellStream Isolation Technology™, helping to deliver consistent, predictable results in your drug metabolism studies and other biological assays.

Pure, highly viable hepatocytes isolated using our CellStream Isolation Technology™

10 donor hepatocytes, 5 male and 5 female in each vial

Verified enzymatic and pathway activity

CellStream™ Isolation Technology
HEP10™ Pooled Human Hepatocytes are made using our novel patent-pending CellStream Isolation Technology™. This process eliminates the disadvantages of density gradient fractionation prior to cryopreservation of the pool. Instead, we gently isolate and purify the pre-screened, high-viability, and metabolically-active hepatocytes from other cells and debris. The result is a remarkably pure pooled hepatocyte preparation with high viability for use in drug metabolism studies and other biological assays.

10 Donors in One Vial
Each vial of HEP10™ Pooled Human Hepatocytes contains hepatocytes from ten individual donors, 5 female and 5 male donors. Custom HEP10 lots can also be prepared from our broad array of high-quality, single-donor cells. Large lots are also available for extensive studies.

Verified Activity
Each pool is characterized for CYP1A2, CYP2B6, CYP2C8, CYP2C9, CYP2C19, CYP2D6, CYP2E1, CYP3A4, CYP3A4⁄5, FMO activity, and NTCP, OATP1B3, and OATP transporter pathways.

Ready for Your Drug Metabolism Experiments
HEP10™ Pooled Human Hepatocytes are useful in a wide variety of applications, including intrinsic clearance, transport, toxicology, biochemistry and cell biology studies.,

Note:
These products require shipment in LN₂ vapor dewars therefore additional fees may apply.

Specifications

• Cell Passage Number: Passage 0
• Cell Type: Hepatocytes
• Form: Cryopreserved
• Species: Human
• Format: Tube
• Product Line: Gibco™
• Quantity: 1.5 mL

• Content And Storage: Store in a cryostorage dewar or -135°C freezer.
• Culture Type: Suspension Cell Culture
• Gender: Unisex
• Donor Source: Pooled
• No. of Cells: 4-8 x 10⁶
• Product Type: Hepatocytes
• Tested For: Phase I and II Enzyme Activity, Transporter Suspension Uptake, Viability ≥75%

For Research Use Only. Not for use in diagnostic procedures.