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Enzo Life Sciences Gabexate . mesylate (50mg). CAS: 56974-61-9
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Supplier:  Enzo Life Sciences BMLPI1440050

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A competitive, reversible inhibitor of serine proteases tryptase (Ki=3.4nM), thrombin (Ki=500nM), uPA (Ki=1.3µM), plasmin (Ki=1.5µM), trypsin (Ki=2µM), factor Xa (Ki=2µM). At higher concentrations it inhibits kallikrein-1 (Ki=2.6mM), C1 esterase (IC50=520µM), as well as phospholipase A2 (IC50=500µM), rat iNOS (Ki=5mM) and cNOS (Ki=150µM), and swine kidney copper amine oxidase (Ki=27µM), but not chymotrypsin. Has been used in tissue culture and in vivo. In clinical use for pancreatitis. Purity: ≥98% (HPLC). Solubility: Soluble in water (25 mg/ml). Long Term Storage: -20°C.

Catalog No. 50-201-1485


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