Thermo Scientific Chemicals Finasteride, 98%

Description

Finasteride, CAS # 98319-26-7, is a 5α-reductase inhibitor that blocks conversion of testosterone and inhibits neurosteroid production.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Finasteride is an inhibitor of the enzyme 5α-reductase, which converts testosterone to dihydrotestosterone (DHT)

• Finasteride also has been explored in neuroscience, as 5α-reductase enzymes are present in the central nervous system

• Finasteride has been seen to cross the blood-brain barrier and block production of neurosteroids

Applications

• Finasteride is mainly used in studies of prostate hyperplasia and tumors in mice, and can be studied in vitro or in vivo for its effects on hyperplasia, proliferation, and antioxidant activity

• Its activity has also been explored in brain, liver and testis tissues

• In vivo injection of finasteride has been shown to decrease neurogenesis and influence neuronal plasticity in mice

Specifications

Chemical Identifiers

• CAS: 98319-26-7
• Molecular Formula: C₂₃H₃₆N₂O₂
• Molecular Weight (g/mol): 372.54
• InChI Key: DBEPLOCGEIEOCV-WSBQPABSSA-N
• Synonym: finasteride, proscar, propecia, finastid, prostide, chibro-proscar, finasterida, finasteridum, finpecia, finasteridum inn-latin
• PubChem CID: 57363
• ChEBI: CHEBI:5062
• IUPAC Name: (1S,3aS,3bS,5aR,9aR,9bS,11aS)-N-tert-butyl-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide
• SMILES: CC12CCC3C(C1CCC2C(=O)NC(C)(C)C)CCC4C3(C=CC(=O)N4)C

• Melting Point: 252.0°C to 254.0°C
• Infrared Spectrum: Authentic
• Assay Percent Range: 97.5% min. (HPLC)
• Quantity: 5 g
• Solubility Information: Solubility in water: very slightly soluble.
• Formula Weight: 372.54
• Percent Purity: 98%
• Chemical Name or Material: Finasteride

Safety and Handling

Hazard Category	GHS Signal Word: Danger
Hazard Statement	GHS H Statement Harmful if swallowed. May damage the unborn child.
Precautionary Statement	GHS P Statement Wash face,hands and any exposed skin thoroughly after handling. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Obtain special instructions before use. Use personal protective equipment as

SDS

RUO – Research Use Only