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Thermo Scientific™ 5-Fluoroorotic Acid
Detect expression of the URA3 gene, which encodes orotine-5'-monophosphate (OMP) dicarboxylase with Thermo Scientific™ 5-Fluoroorotic Acid, used in yeast molecular genetics.
$144.70 - $529.00
Specifications
| Chemical Name or Material | 5-Fluoroorotic Acid |
|---|---|
| Product Type | 5-Fluoroorotic Acid |
| Form | Powder |
Description
5-Fluoroorotic Acid is a yeast with an active URA3 gene (Ura+) converts 5-FOA to fluorodeoxyuridine, which is toxic to cells (see the scheme below). Yeast strains carrying a mutation in the URA3 gene grow in the presence of 5-FOA if the media is supplemented with uracil. 5-FOA is frequently used in experiments with Saccharomyces cerevisiae (URA3), Schizosaccharomyces pombe (URA4 and URA5), Candida albicans (URA3), and E. coli (pyrF).
Convertion of 5-FOA to fluorodeoxyuridine
Convertion of 5-FOA to fluorodeoxyuridine
Specifications
| 5-Fluoroorotic Acid | |
| 5-Fluoroorotic Acid | |
| Powder |
For Research Use Only. Not for use in diagnostic procedures.
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