Ethyl difluoroacetate, 98%, Thermo Scientific Chemicals

Description

Ethyl difluoroacetate is used in pharmaceutical intermediates, acrylization oxidation and halogenating reaction of catalyst. Also ethyl difluoroacetate is used in preparing pyrrazolo-pyrimidine derivatives.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Ethyl difluoroacetate is used in pharmaceutical intermediates, acrylization oxidation and halogenating reaction of catalyst. Also ethyl difluoroacetate is used in preparing pyrrazolo-pyrimidine derivatives.

Solubility
Slightly soluble in water

Notes
Hygroscopic. Store away from strong oxidizing agents. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.

Specifications

Chemical Identifiers

• CAS: 454-31-9
• Molecular Formula: C4H6F2O2
• Molecular Weight (g/mol): 124.087
• MDL Number: MFCD00013578
• InChI Key: GZKHDVAKKLTJPO-UHFFFAOYSA-N
• Synonym: ethyl difluoroacetate, acetic acid, difluoro-, ethyl ester, difluoroacetic acid ethyl ester, ethyldifluoroacetate, ethyl difluoroacetic, ethyl difluoro acetate, difluoro-acetic acid ethyl ester, ethyl difluoroacetic acid, acetic acid, 2,2-difluoro-, ethyl ester, ethyldifluoracetat
• PubChem CID: 9961
• IUPAC Name: ethyl 2,2-difluoroacetate
• SMILES: CCOC(=O)C(F)F

• Density: 1.242
• Boiling Point: 98°C to 99°C
• Flash Point: 25°C (77°F)
• Refractive Index: 1.3475
• Quantity: 100 g
• UN Number: UN2924
• Beilstein: 1748597
• Solubility Information: Slightly soluble in water
• Formula Weight: 124.09
• Percent Purity: 98%
• Chemical Name or Material: Ethyl difluoroacetate

Safety and Handling

Hazard Category	H226-H314
Hazard Statement	GHS H Statement H314-H318-H226 Causes severe skin burns and eye damage. Causes serious eye damage. Flammable liquid and vapor.
Precautionary Statement	P210-P233-P240-P241-P242-P243-P260-P264b-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P370+P378q-P501c
DOTInformation	Transport Hazard Class: 3; Packing Group: III; Proper Shipping Name: FLAMMABLE LIQUIDS, CORROSIVE, N.O.S.
EINECSNumber	207-223-4
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only