(Ethoxycarbonylmethylene)triphenylphosphorane, 98+%, Thermo Scientific Chemicals

Description

(Ethoxycarbonylmethylene)triphenylphosphoran is used as a Wittig reagent in organic synthesis. It is used in the preparation of indole from o-nitrobenzaldehydes, coumarins from o-hydroxy acetophenone. It acts as an inhibitor and inhibits the activity of cholinesterase.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
(Ethoxycarbonylmethylene)triphenylphosphoran is used as a Wittig reagent in organic synthesis. It is used in the preparation of indole from o-nitrobenzaldehydes, coumarins from o-hydroxy acetophenone. It acts as an inhibitor and inhibits the activity of cholinesterase.

Solubility
Soluble in organic solvents. Insoluble in water.

Notes
Air sensitive. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 1099-45-2
• Molecular Formula: C22H21O2P
• Molecular Weight (g/mol): 348.38
• MDL Number: MFCD00009183
• InChI Key: IIHPVYJPDKJYOU-UHFFFAOYSA-N
• Synonym: carbethoxymethylene triphenylphosphorane, ethyl triphenylphosphoranylidene acetate, triphenylcarbethoxymethylenephosphorane, acetic acid, triphenylphosphoranylidene-, ethyl ester, ethyl 2-triphenylphosphoranylidene acetate, ethoxycarbonylmethylene triphenylphosphorane, carboethoxymethylidenetriphenylphosphorane, ethyl triphenylphosphoranilidene acetate, carbethoxytriphenylphosphonium methylide, carbethoxymethylidenetriphenylphosphorane
• PubChem CID: 70670
• IUPAC Name: ethyl 2-(triphenyl-$l^{5}-phosphanylidene)acetate
• SMILES: CCOC(=O)C=P(C1=CC=CC=C1)(C1=CC=CC=C1)C1=CC=CC=C1

• Melting Point: 126°C to 130°C
• Quantity: 250 g
• Beilstein: 754639
• Sensitivity: Air sensitive
• Solubility Information: Soluble in organic solvents. Insoluble in water.
• Formula Weight: 348.38
• Percent Purity: ≥98%
• Chemical Name or Material: (Ethoxycarbonylmethylene)triphenylphosphorane

Safety and Handling

EINECSNumber	214-151-7
TSCA	Yes
Recommended Storage	Keep cold; Store under Argon

SDS

RUO – Research Use Only