Ellagic acid hydrate, 97%, may cont. up to 12% water, Thermo Scientific Chemicals

Description

Ellagic acid used as selective, ATP-competitive inhibitor of casein kinase 2. Exhibits antitumor activity and inhibits glutathione S-transferase. It is also used as a Topo I and II, FGR, GSK, and PKA inhibitor.Commonly occurring plant polyphenol, inhibitor of glutathione S-transferase. Used for the assay of factor XIIa in plasma.Contact activation in blood coagulation.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Ellagic acid used as selective, ATP-competitive inhibitor of casein kinase 2. Exhibits antitumor activity and inhibits glutathione S-transferase. It is also used as a Topo I and II, FGR, GSK, and PKA inhibitor.Commonly occurring plant polyphenol, inhibitor of glutathione S-transferase. Used for the assay of factor XIIa in plasma.Contact activation in blood coagulation.

Solubility
Slightly soluble in water. Soluble in 1M sodium hydroxide (10 mg/ml), EtOH, and pyridine.

Notes
Air sensitive and light sensitive. Store under dry inert gas. Store in cool dry place in tightly closed container. Store in dark and away form air.

Specifications

Chemical Identifiers

• CAS: 476-66-4
• Molecular Formula: C14H6O8
• Molecular Weight (g/mol): 302.19
• MDL Number: MFCD00006914
• InChI Key: AFSDNFLWKVMVRB-UHFFFAOYSA-N
• Synonym: ellagic acid, benzoaric acid, lagistase, eleagic acid, alizarine yellow, elagostasine, 2,3,7,8-tetrahydroxychromeno 5,4,3-cde chromene-5,10-dione, ellagic acid dihydrate, llagic acid, acide ellagique
• PubChem CID: 5281855
• ChEBI: CHEBI:4775
• IUPAC Name: 6,7,13,14-tetrahydroxy-2,9-dioxatetracyclo[6.6.2.0⁴,¹⁶.0¹¹,¹⁵]hexadeca-1(15),4(16),5,7,11,13-hexaene-3,10-dione
• SMILES: OC1=CC2=C3C(OC(=O)C4=CC(O)=C(O)C(OC2=O)=C34)=C1O

• Melting Point: 450°C (decomposition)
• Quantity: 100 g
• Beilstein: 47549
• Sensitivity: Air and light sensitive
• Merck Index: 14,3547
• Solubility Information: Slightly soluble in water. Soluble in 1M sodium hydroxide (10mg/ml),EtOH,and pyridine.
• Formula Weight: 302.20 (Anhydrous)
• Percent Purity: 97%
• Assay: may cont. up to 12% water
• Chemical Name or Material: Ellagic acid hydrate

Safety and Handling

Hazard Category	H315-H319-H335
Hazard Statement	GHS H Statement H315-H319-H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
EINECSNumber	207-508-3
RTECSNumber	DJ2620000
TSCA	No
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only