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Enzo Life Sciences Dimethyl-W84 dibromide (5mg). CAS: 402475-33-6
Supplier: Enzo Life Sciences ALX550400M005
Very potent allosteric modulator of muscarinic receptors, selective for M2-receptors. Retards the dissociation of the antagonist N-methylscopolamine. Affinity for the free receptor is about 10-fold higher than with W84 (ALX-550-399). pKA=7.08, p(αKA)=6.75, pEC50,diss=6.77. Alternative name: N,N-Bis[3-(1,3-dihydro-5-methyl-1,3-dioxo-2H-isoindol-2-yl)propyl]-N,N,N,N-tetramethyl-1,6-hexanediamminium dibromide. Purity: ≥98% (HPLC). Solubility: Soluble in DMSO, water or aqueous buffer. Long Term Storage: +4°C.
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