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DIDS, Tocris Bioscience™

Catalog No. 452350
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Quantity:
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Chloride channel blocker; TRPV1 modulator; RAD51 recombinase inhibitor

ClC-Ka chloride channel blocker (IC50 = 100 μM). Blocks the maxi chloride channel in apical membranes from human placenta. Displays antagonistic activity at TRPM4 and TRPC4 channels; potentiates agonist-induced TRPV1 currents (IC50 = 4.88 μM in rat DRG neurons). Inhibits RAD51 recombinase activity (KD = 2 μM).

Chemical Identifiers

CAS 67483-13-0
Molecular Formula C16H8N2Na2O6S4
Molecular Weight (g/mol) 498.468
InChI Key GEPAYBXVXXBSKP-SEPHDYHBSA-L
Synonym dids, unii-1vfrq7416a, disodium 4,4'-diisothiocyanato-2,2'-stilbenedisulfonate, 4,4'-diisothiocyanato-2,2'-stilbenedisulfonic acid disodium salt, 4,4'-diisothiocyano-2,2'-stilbenedisulfonic acid, disodium salt, disodium 5-isothiocyanato-2-e-2-4-isothiocyanato-2-sulfonatophenyl ethenyl benzenesulfonate, spectrum1505164, 4 4'-diisothiocyanato-2 2'-stilbenedisu, disodium 4,4'-diisothiocyanatostilbene-2,2'-disulfonate, disodium 4,4'-diisothiocyanato-2,2'-stilbenedisulfonate, e
PubChem CID 5702690
IUPAC Name disodium;5-isothiocyanato-2-[(E)-2-(4-isothiocyanato-2-sulfonatophenyl)ethenyl]benzenesulfonate
SMILES C1=CC(=C(C=C1N=C=S)S(=O)(=O)[O-])C=CC2=C(C=C(C=C2)N=C=S)S(=O)(=O)[O-].[Na+].[Na+]

Specifications

Quantity 50 mg
Formula Weight 498.48
Percent Purity >95%
Chemical Name or Material DIDS

Safety and Handling

Recommended Storage Store at +4°C
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