Dibenzyl phosphite, 90+%, Thermo Scientific Chemicals

Description

Dibenzyl phosphite is used for the phosphorylation of phenols involves reaction in the presence of N-ethyldiisopropylamine and DMAP to give the dibenzyl phenyl phosphate. It is used in the preparation of phenylalkylphosphonamidates which are then used as probes for a hydrophobic binding register in prostate-specific membrane antigen.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Dibenzyl phosphite is used for the phosphorylation of phenols involves reaction in the presence of N-ethyldiisopropylamine and DMAP to give the dibenzyl phenyl phosphate. It is used in the preparation of phenylalkylphosphonamidates which are then used as probes for a hydrophobic binding register in prostate-specific membrane antigen.

Solubility
Soluble in DMSO, Methanol. Reacts with water.

Notes
Store at 4°C. Moisture Sensitive. Incompatible with moisture and oxidizing agents. Store under dry inert gas. Store away from oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 17176-77-1
• Molecular Formula: C14H14O3P
• Molecular Weight (g/mol): 261.24
• MDL Number: MFCD00004774
• InChI Key: RQKYHDHLEMEVDR-UHFFFAOYSA-N
• Synonym: dibenzyl phosphonate, phosphonic acid dibenzyl ester, unii-1o720l5h5a, phosphonic acid, bis phenylmethyl ester, dibenzylphosphit, dibenzylphosphonate, phosphonic acid bis phenylmethyl ester, oxo-bis phenylmethoxy phosphanium, mibxhgzaarwagi-uhfffaoysa-n, dibenzyl phosphite, technical grade
• PubChem CID: 6334615
• IUPAC Name: oxo-bis(phenylmethoxy)phosphanium
• SMILES: O=[P+](OCC1=CC=CC=C1)OCC1=CC=CC=C1

• Density: 1.187
• Boiling Point: 110°C to 120°C (0.1 mmHg)
• Flash Point: >110°C (230°F)
• Odor: Odorless
• Refractive Index: 1.554
• Quantity: 100 g
• Beilstein: 1982794
• Sensitivity: Moisture sensitive
• Merck Index: 14,3014
• Solubility Information: Soluble in DMSO,Methanol. Reacts with water.
• Formula Weight: 262.25
• Percent Purity: ≥90%
• Chemical Name or Material: Dibenzyl phosphite

Safety and Handling

Hazard Category	H315-H319-H335
Hazard Statement	GHS H Statement H315-H319-H317 Causes skin irritation. Causes serious eye irritation. May cause an allergic skin reaction.
Precautionary Statement	P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
EINECSNumber	241-226-1
TSCA	No
Recommended Storage	Store under Nitrogen

SDS

RUO – Research Use Only