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Enzo Life Sciences Diacylglycerol Kinase Inhibitor II (R59 949) (25mg). CAS: 120166-69-0
Supplier: Enzo Life Sciences ALX430028M025
Inhibitor of diacylglycerol kinase in intact cells (IC50=0.12µM) and in isolated membranes (IC50=0.3µM). More potent analog of R59 022 (ALX-430-027). Useful for elucidating roles of protein kinase C (PKC). Alternative name: 3-[2-[4-[bis(4-Fluorophenyl)methylene]-1-piperidinyl]ethyl]-2,3-dihydro-2-thioxo-4(1H)-quinazolinone. Purity: ≥98% (HPLC). Solubility: Soluble in dichloromethane, ethyl acetate, tetrahydro-furan, DMSO (33mg/ml) or dimethyl formamide; almost insoluble in water. Long Term Storage: +4°C.
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