CYP3A5 Monoclonal Antibody (F18 P3 B6), Invitrogen™

Mouse Monoclonal Antibody

Supplier:  Thermo Scientific MA3033

Catalog No. 01-670-130

Description

MA3-033 detects Cytochrome P450 3A5 from HEK293 and HepG2 human cell lines, and from bovine liver and pancreas samples. MA3-033 has been successfully used in Western blot applications. By Western blot, this antibody detects a ∽54 kDa band representing Cytochrome P450 3A5. The MA3-033 immunogen is a synthetic peptide corresponding to residues E S R D G T L S G E, conjugated to ovalbumin.

CYP3A5 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. The enzyme metabolizes drugs such as nifedipine and cyclosporine as well as the steroid hormones testosterone, progesterone and androstenedione.

Specifications

• Antigen: CYP3A5
• Classification: Monoclonal
• Concentration: Conc. Not Determined
• Formulation: ascites with 0.05% sodium azide
• Gene Accession No.: P20815
• Gene Symbols: CYP3A5
• Immunogen: Synthetic peptide corresponding to residues E S R D G T L S G E, conjugated to ovalbumin.
• Regulatory Status: RUO
• Gene ID (Entrez): 1577, 282214, 526682
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
• Clone: F18 P3 B6
• Conjugate: Unconjugated
• Gene: CYP3A5
• Gene Alias: aryl hydrocarbon hydroxylase; CP35; CYP3A28; CYP3A4; CYP3A5; CYPIIIA28; CYPIIIA5; cytochrome P450; cytochrome P450 3A28; cytochrome P450 3A5; cytochrome P450 family 3 subfamily A member 5; cytochrome P450 HLp2; cytochrome P450, family 3, subfamily A, polypeptide 5; cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4; cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 5; cytochrome P450-PCN3; flavoprotein-linked monooxygenase; HLp2; microsomal monooxygenase; P450PCN3; P450-PCN3; PCN3; Unknown (protein for MGC:127840); xenobiotic monooxygenase
• Host Species: Mouse
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Bovine, Human
• Product Type: Antibody
• Isotype: IgG1