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  8. Clofibrate, 95+%, Thermo Scientific Chemicals

Clofibrate, 95+%, Thermo Scientific Chemicals

Catalog No. AAJ6034222
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Quantity:
1 g
5 g
25 g
100 g

Description

It is a lipid-lowering agent used for controlling the high cholesterol and triacylglyceride level in the blood. It increases lipoprotein lipase activity to promote the conversion of VLDL to LDL, and hence reduce the level of VLDL. It can increase the level of HDL as well. Clofibrate is a ligand agonist for PPARα (peroxisome proliferator-activated receptor α), or an inducer of cytochromes P450’s CYP4A1 and CYP4A3.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble to 100 mM in DMSO.

Notes
Store in cool, dry place in a tightly sealed container. Store away from oxidizing agents, heat, bases. Store in refrigerator.

Chemical Identifiers

CAS 637-07-0
Molecular Formula C12H15ClO3
Molecular Weight (g/mol) 242.70
MDL Number MFCD00000615
InChI Key KNHUKKLJHYUCFP-UHFFFAOYSA-N
Synonym clofibrate, ethyl clofibrate, clofibratum, clofibrato, atromid-s, miscleron, atromid, liprin, epib, angiokapsul
PubChem CID 2796
ChEBI CHEBI:3750
IUPAC Name ethyl 2-(4-chlorophenoxy)-2-methylpropanoate
SMILES CCOC(=O)C(C)(C)OC1=CC=C(Cl)C=C1

Specifications

Density 1.14
Boiling Point 154°C to 156°C
Flash Point 113°C (235°F)
Refractive Index 1.5
Quantity 100 g
UN Number UN3082
Beilstein 1913459
Merck Index 14,2377
Solubility Information Soluble to 100 mM in DMSO.
Formula Weight 242.7
Percent Purity ≥95%
Physical Form Liquid
Chemical Name or Material Clofibrate
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Safety and Handling

Hazard Category H302-H315-H318-H335
Hazard Statement GHS H Statement
H318-H302-H335-H315
Causes serious eye damage.
Harmful if swallowed.
May cause respiratory irritation.
Causes skin irritation.
Precautionary Statement P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P310-P312-P330-P332+P313-P362-P501c
DOTInformation Transport Hazard Class: 9; Packing Group: III; Proper Shipping Name: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID, N.O.S.
EINECSNumber 211-277-4
RTECSNumber UE9480000
TSCA No
Recommended Storage Keep cold
SDS

RUO – Research Use Only

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