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Eurofins Discoverx PathHunter CHO-K1 AGTRL1 β-Arrestin Cell Line, 2 vials. (93-0250C2)

Supplier:  Eurofins Discoverx 930250C2

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The PathHunter AGTRL1 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. PACAP) based activation of AGTRL1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged AGTRL1 and EA-tagged β-Arrestin-2. Activation of AGTRL1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.

Catalog No. 50-200-0078


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