Chloramphenicol (Crystalline Powder), Fisher BioReagents

Description

For selecting transformed cells containing chloramphenicol resistance genes

Used as a selection agent for transformed cells containing chloramphenicol resistance genes. Mode of Action: Inhibits translation on the 50S ribosomal subunit at the peptidyltransferase step (elongation inhibition).

Specifications

Chemical Identifiers

• CAS: 56-75-7
• Molecular Formula: C11H12Cl2N2O5
• Molecular Weight (g/mol): 323.126
• InChI Key: WIIZWVCIJKGZOK-RKDXNWHRSA-N
• Synonym: Chloromycetin, D-(?)-threo-2, 2-Dichloro-N-[?-hydroxy-?-(hydroxymethyl)-?-(4-nitrophenyl)ethyl]acetamide
• PubChem CID: 5959
• ChEBI: CHEBI:17698
• IUPAC Name: 2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide
• SMILES: C1=CC(=CC=C1C(C(CO)NC(=O)C(Cl)Cl)O)[N+](=O)[O-]

• Type: Chloramphenicol
• Physical Form: Solid
• pH: 5 to 7
• Melting Point: 149°C
• Packaging: Poly Bottle
• Specific Rotation: Inclusive between 17° (+ or -)
• Color: White
• Quantity: 100 g
• Assay Percent Range: 97%
• Merck Index: 15, 2077
• Formula Weight: 323.13
• Chemical Name or Material: Chloramphenicol

Safety and Handling

Hazard Statement	WARNING!
Precautionary Statement	Emergency Overview Suspect cancer hazard. May cause skin, eye, and respiratory tract irritation. Use personal protective equipment. Use only under a chemical fume hood. Wash off immediately with plenty of water for at least 15 minutes. Immediate medical attention is required. Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Immediate medical attention is required. Move to fresh air. If breathing is difficult, give oxygen. Do not use mouth-to-mouth resuscitation if victim ingested or inhaled the substance; induce artifici. Immediate medical attention is required. Immediate medical attention is required. Do not induce vomiting. NFPA Health:2 Flammability:0 Instability:0
Recommended Storage	RT

SDS