CD3 Mouse, anti-Human, RB780, Clone: UCHT1 (also known as UCHT-1; UCHT 1), BD Horizon™

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 568678

Catalog No. BDB568678

Description

The UCHT1 monoclonal antibody specifically binds to the human CD3ε-chain, a 20-kDa subunit of the CD3/T cell antigen receptor complex. CD3ε is expressed on 70-80% of normal human peripheral blood lymphocytes and 60-85% of thymocytes. Studies from the HLDA Workshop show that this antibody is mitogenic for CD3ε-positive cells when used in conjunction with costimulatory agents such as pokeweed mitogen or anti-CD28 antibody. CD3 plays a central role in signal transduction during antigen recognition. The UCHT1 antibody stains both surface and intracellular CD3ε unlike the other CD3 clone, HIT3a, that stains only extracellular CD3ε.

Specifications

• Antigen: CD3
• Clone: UCHT1 (also known as UCHT-1; UCHT 1)
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide
• Immunogen: Human infant thymocytes and peripheral blood lymphocytes from a Sézary Syndrome donor
• Regulatory Status: RUO
• Gene ID (Entrez): 916
• Content And Storage: Refrigerate (2°C to 8°C)

• Applications: Flow Cytometry
• Conjugate: RB780
• Host Species: Mouse
• Quantity: 100 Tests
• Primary or Secondary: Secondary
• Target Species: Human
• Isotype: IgG1 κ