CD11a (LFA-1A) Mouse, anti-Human, RB780, Clone: HI111, BD Horizon™

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 568776

Catalog No. BDB568776

Description

The HI111 monoclonal antibody specifically binds to CD11a, the 180 kDa integrin α chain. This type I transmembrane glycoprotein associates with CD18 (integrin β2) to form the heterodimeric glycoprotein CD11a/CD18. This heterodimer is also known as the lymphocyte (leukocytes) function associated antigen-1 (LFA-1) that is expressed on all leukocytes. LFA-1 is an adhesion molecule involved in lymphocyte and granulocyte functions. LFA-1 mediates adhesion of lymphoid cells to the vascular endothelium in association with its ligand, and the intracellular adhesion molecule-1 (ICAM-1), CD54. Other ligands are ICAM-2 (CD102) and ICAM-3 (CD50).

Specifications

• Antigen: CD11a (LFA-1A)
• Clone: HI111
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide
• Quantity: 100 Tests
• Primary or Secondary: Secondary
• Target Species: Human
• Isotype: IgG1 κ

• Applications: Flow Cytometry
• Conjugate: RB780
• Host Species: Mouse
• Regulatory Status: RUO
• Gene ID (Entrez): 3683
• Content And Storage: Refrigerate (2°C to 8°C)