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MilliporeSigma™ Calbiochem™ Sumanirole Maleate

An extremely selective dopamine D2 receptor agonist (Ki =

Supplier:  MilliporeSigma™ 5.05896.0001

Catalog No. 50-589-60001


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Description

Description

An extremely selective dopamine D2 receptor agonist (Ki = 9nM). Commonly used in Parkinson′s Disease models and to reproduce cocaine′s discriminative stimulus effects. Sumanirole has greater than 200-fold selectivity for the D2 receptor subtype versus the other dopamine receptor subtypes in radioligand binding assays. In cell-based assays, sumanirole is a fully efficacious agonist, with EC50 values between 17 and 75 nM. In animals, sumanirole elicits many physiological responses attributed to D2-like receptor function.
Specifications

Specifications

Protect from light
Solid
98% by HPLC
C11H13N3O·C4H4O4
5 mg
Off-white
D2
DMSO
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