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  8. BX 513 hydrochloride, Tocris Bioscience™

BX 513 hydrochloride, Tocris Bioscience™

Catalog No. 276950
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Selective CCR1 antagonist

Selective CCR1 receptor antagonist (Ki values are 0.04, > 10, > 10 and > 10 nM for CCR1, CCR5, CXCR2 and CXCR4 receptors respectively). Inhibits MIP-1α-induced intracellular calcium mobilization (IC50 = 2.5 μM). Also a full inverse agonist at US28, a HCMV-encoded chemokine receptor.

Chemical Identifiers

CAS 1216540-18-9
Molecular Formula C28H30Cl2N2O
Molecular Weight (g/mol) 481.461
InChI Key SSZWNUGWOGONQJ-UHFFFAOYSA-N
Synonym bx 513 hydrochloride, bx-513 hydrochloride, 1-piperidinepentanenitrile,4-4-chlorophenyl-4-hydroxy-a,a-diphenyl-,hydrochloride, 4-4-chlorophenyl-4-hydroxy-?,?-diphenyl-1-piperidinepentanenitrile hydrochloride, 5-4-4-chlorophenyl-4-hydroxypiperidin-1-yl-2,2-diphenylpentanenitrile hydrochloride, 5-4-4-chlorophenyl-4-hydroxypiperidin-1-yl-2,2-diphenylpentanenitrile-hydrogen chloride 1/1
PubChem CID 56972186
IUPAC Name 5-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-2,2-diphenylpentanenitrile;hydrochloride
SMILES C1CN(CCC1(C2=CC=C(C=C2)Cl)O)CCCC(C#N)(C3=CC=CC=C3)C4=CC=CC=C4.Cl

Specifications

Quantity 50 mg
Formula Weight 481.46
Percent Purity >99%
Chemical Name or Material BX 513 hydrochloride

Safety and Handling

Recommended Storage Desiccate at +4°C
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