Thermo Scientific Chemicals Burgess Reagent, 96%

Description

Burgess reagent is a selective dehydrating reagent used in organic synthesis. It is used to convert secondary and tertiary alcohol, with an adjacent proton, into alkenes. Burgess reagent is also utilized to promote great synthetic values in medicinal chemistry. It has been used in dehydration of primary amides, formamides and primary nitroalkanes to generate nitriles, isocyanides and nitrile oxides respectively. It forms urethanes when it reacts with primary alcohols.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Burgess reagent is a selective dehydrating reagent used in organic synthesis. It is used to convert secondary and tertiary alcohol, with an adjacent proton, into alkenes. Burgess reagent is also utilized to promote great synthetic values in medicinal chemistry. It has been used in dehydration of primary amides, formamides and primary nitroalkanes to generate nitriles, isocyanides and nitrile oxides respectively. It forms urethanes when it reacts with primary alcohols.

Solubility
Soluble in organic solvents.

Notes
Store in cool place. Moisture sensitive. Incompatible with strong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 29684-56-8
• Molecular Formula: C8H18N2O4S
• Molecular Weight (g/mol): 238.30
• MDL Number: MFCD00077815
• InChI Key: YSHOWEKUVWPFNR-UHFFFAOYSA-N
• Synonym: methoxycarbonylsulfamoyl triethylammonium hydroxide, burgess reagent, carbomethoxysulfamoyltriethylammonium hydroxide, methoxycarbonylsulfamoyltriethylammonium hydroxide, methoxycarbonylsulphamoyltriethylammonium hydroxide, methoxy-carbonylsulfamoyltriethylammonium hydroxide, methoxycarbonylsulfa-moyl-triethylammonium hydroxide, methoxycarbonylsulphamoyl-triethylammonium hydroxide
• PubChem CID: 11032497
• SMILES: CC[N+](CC)(CC)S(=O)(=O)[N-]C(=O)OC

• Melting Point: 72°C to 82°C
• Quantity: 25 g
• Beilstein: 1432131
• Sensitivity: Moisture sensitive
• Solubility Information: Soluble in organic solvents.
• IUPAC Name: triethyl(methoxycarbonylsulfamoyl)azanium;hydroxide
• Formula Weight: 238.3
• Percent Purity: 96%
• Chemical Name or Material: Burgess Reagent

Safety and Handling

Hazard Category	H315-H319-H335
Hazard Statement	GHS H Statement H315-H319-H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
TSCA	No
Recommended Storage	Store at -20°C

SDS

RUO – Research Use Only