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Tocris Bioscience™ BIX 02189

Selective MEK5 and ERK5 inhibitor

Supplier:  Tocris Bioscience™ 4842/10

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Catalog No. 48-421-0


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Description

Description

BIX 02189 is a selective MEK5 and ERK5 inhibitor (IC50 values are 1.5 and 59 nM respectively). Inhibits sorbitol-induced ERK5 phosphorylation in HeLa cells. Selective for MEK5 and ERK5 over MEK1/2, ERK1/2 and a panel of 87 kinases. Induces apoptosis in acute myeloid leukemia tumor cells.
Specifications

Specifications

>98%
BIX 02189
BIX 02189
10 mg
440.54
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