Azathioprine, Thermo Scientific Chemicals

Description

Azathioprine is an immunosuppressive purine antimetabolite. The mechanism of action of azathioprine is as a nucleic acid synthesis inhibitor. It has shown promise in treatment of alopecia areata (autoimmune hair loss), with no difference in effectiveness between genders.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble in Dichloromethane and dimethyl sulfoxide.

Notes
Store at -20°C. Incompatible with oxidizing agents. Protect from heat.

Specifications

Chemical Identifiers

• CAS: 446-86-6
• Molecular Formula: C9H7N7O2S
• Molecular Weight (g/mol): 277.262
• MDL Number: MFCD00069203
• InChI Key: LMEKQMALGUDUQG-UHFFFAOYSA-N
• Synonym: azathioprine, azothioprine, imuran, azathioprin, azatioprin, azamun, azanin, imurel, ccucol, imurek
• PubChem CID: 2265
• ChEBI: CHEBI:2948
• IUPAC Name: 6-(3-methyl-5-nitroimidazol-4-yl)sulfanyl-7H-purine
• SMILES: CN1C=NC(=C1SC2=NC=NC3=C2NC=N3)[N+](=O)[O-]

• Color: Yellow
• Quantity: 10 g
• Merck Index: 14,902
• Solubility Information: Soluble in Dichloromethane and dimethyl sulfoxide.
• Formula Weight: 277.26
• Physical Form: Crystalline Powder
• Chemical Name or Material: Azathioprine

Safety and Handling

Hazard Category	H302-H315-H319-H335-H350
Hazard Statement	GHS H Statement H350-H302-H315-H319-H335 May cause cancer. Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P201-P202-P261-P264b-P270-P271-P280i-P281-P301+P312-P302+P352-P304+P340-P305+P351+P338-P308+P313-P330-P332+P313-P362-P501c
EINECSNumber	207-175-4
RTECSNumber	UO8925000
TSCA	No
Recommended Storage	Store at -20°C

SDS

RUO – Research Use Only