AP2 alpha Monoclonal Antibody (3B5), Invitrogen™

Mouse Monoclonal Antibody

Supplier:  Thermo Scientific MA1872

Catalog No. 01-670-128

Description

MA1-872 detects AP-2 from human, mouse, and chicken samples. MA1-872 has been successfully used in Western blot, immunoprecipitation, and immunofluorescence applications. By Western blot, this antibody detects a 45-50 kDa band representing AP-2. For Western blotting, block with BSA only (not milk). The MA1-872 immunogen is the N-terminus of human AP2a.

TFAP2A is a sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limbs and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. TFAP2A is the only AP-2 protein required for early morphogenesis of the lens vesicle.

Specifications

• Antigen: AP2 alpha
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1mg/mL BSA and 0.05% sodium azide
• Gene Accession No.: P05549, P34056
• Gene Symbols: TFAP2A
• Immunogen: N-terminus of human AP2a.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Chicken, Human, Mouse
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot
• Clone: 3B5
• Conjugate: Unconjugated
• Gene: TFAP2A
• Gene Alias: activating enhancer-binding protein 2 alpha; activating enhancer-binding protein 2-alpha; Activator protein 2; activator protein 2 alpha variant 4; activator protein 2 alpha variant 6; activator protein 2 alpha variant 7; AP2; AP-2; Ap-2 (a); AP-2 transcription factor; AP2alpha; AP-2alpha; AP2-alpha; Ap2tf; BOFS; ERF-1; FLJ51761; OTTHUMP00000214240; OTTHUMP00000214243; Tcfap2a; TFAP2; TFAP2A; transcription factor AP2; transcription factor AP-2 alpha; transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha); transcription factor AP-2, alpha; transcription factor AP-2-alpha; transcription factor AP-2-alpha-like; transcription factor; AP-2
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 21418, 395982, 7020
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid