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Eurofins Discoverx Angiotensin II, Human, 5 mg. (92-1077)
Supplier: Eurofins Discoverx 921077
Angiotensin II is an endocrine, autocrine/paracrine, and intracrine hormone formed from the conversion of angiotensin I via angiotensin-converting enzyme (ACE). It increases blood pressure by vasoconstriction, sympathetic nervous stimulation, increased aldosterone biosynthesis, and Gαq protein stimulation in vascular smooth muscle. Also acts as a Na/H exchanger in the proximal tubules of the kidney, increasing blood sodium content and leading to increased blood volume, pressure and pH. Thus ACE inhibitors are considered anti-hypertensives. Provided as 5 mg of dry powder alongside reconstitution buffer. These highly purified, pre-validated control ligands have been used to qualify our InCELL Hunter, PathHunter and cAMP Hunter cell lines as well as our Assay Ready Kits. Ligands are conveniently supplied with a recommended reconstitution buffer. For detailed information and product-specific datasheet, visit www.discoverx.com/ligands.
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