Amikacin (From Kanamycin A, White Crystalline Powder), Fisher BioReagents

Description

• An antibiotic that serves as a selective agent to isolate transformed bacteria
• Amikacin functions as an indirect inhibitor of protein synthesis in prokaryotes by binding to the 30S subunit of ribosomes
• Useful as a selective agent to isolate bacteria that have been transformed with plasmid containing the antibiotic-resistant gene
• Intended for research purposes only; not for manufacturing or commercial use

Specifications

Chemical Identifiers

• CAS: 37517-28-5
• Molecular Formula: C22H43N5O13
• Molecular Weight (g/mol): 585.608
• InChI Key: LKCWBDHBTVXHDL-RMDFUYIESA-N
• Synonym: Lukadin
• PubChem CID: 37768
• ChEBI: CHEBI:2637
• IUPAC Name: (2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-trihydroxyoxan-2-yl]oxy-3-hydroxycyclohexyl]-2-hydroxybutanamide
• SMILES: C1C(C(C(C(C1NC(=O)C(CCN)O)OC2C(C(C(C(O2)CO)O)N)O)O)OC3C(C(C(C(O3)CN)O)O)O)N

• Type: Amikacin
• Physical Form: Solid
• pH: 9.5 to 11.5
• Melting Point: 214°C
• Packaging: Amber Glass
• Potency: > 900μg/mg
• Color: White
• Quantity: 250 mg
• Merck Index: 15, 400
• Solubility Information: completely soluble in water
• Formula Weight: 585.61
• Chemical Name or Material: Amikacin, From Kanamycin A

Safety and Handling

Hazard Statement	CAUTION!
Precautionary Statement	Emergency Overview May cause skin, eye, and respiratory tract irritation. Use personal protective equipment. Ensure adequate ventilation. Wash off immediately with plenty of water for at least 15 minutes. Get medical attention immediately if symptoms occur. Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Obtain medical attention. Move to fresh air. If breathing is difficult, give oxygen. Get medical attention immediately if symptoms occur. Do not induce vomiting. Obtain medical attention. Obtain medical attention. . NFPA Health:1 Flammability:0 Instability:0
TSCA	Not on TSCA inventory: for R and D use only; not for manufacturing or commercial purposes.
Recommended Storage	0° to 5°C, desiccate.

SDS