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(±)-AMG 487, Tocris Bioscience™
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Quantity:
10 mg
50 mg
Description
(±)-AMG 487 is an antagonist of CXCR3; inhibits binding of 125I-IP-10 and 125I-ITAC to CXCR3 (IC50 values are 8.0 and 8.2 nM respectively). Inhibits CXCR3-mediated cell migration by the chemokines IP-10, ITAC and MiG in vitro (IC50 values are 8, 15 and 36 nM respectively). Also shown to inhibit lung metastasis in a mouse model of metastatic breast cancer.
This product is racemic.
Specifications
Specifications
Quantity | 50 mg |
Formula Weight | 603.59 |
Percent Purity | >98% |
Chemical Name or Material | (±)-AMG 487 |
Safety and Handling
Recommended Storage | Store at -20°C |
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