Thermo Scientific™ Acclaim™ Mixed Mode WCX-1 HPLC Columns

Separate cationic molecules with powerful adjustable selectivity control using this mixed-mode reversed-phase and weak cation-exchange LC column.

Separate cationic molecules with powerful adjustable selectivity control using Thermo Scientific™ Acclaim™ Mixed-Mode WCX-1 LC columns. The silica-based stationary phase features a hydrophobic alkyl chain with a carboxyl terminus that provides both hydrophobic reversed-phase and weak cation-exchange properties. This multimode separation mechanism delivers simultaneous separation of basic and neutral compounds. By independently or simultaneously tuning the mobile phase ionic strength, pH, and organic modifier, you can control the selectivity of ionizable and neutral compounds.

Retains and Separates Highly Hydrophilic to Highly Hydrophobic Basic Molecules

• Multimode retention mechanism: reversed-phase, weak cation-exchange, anion-exclusion, and HILIC modes
• Selectivity complementary to C18 reversed-phase columns
• Efficient primary column for a variety of basic analytes; also an ideal column for secondary methods development
• Versatile in applications that require different selectivities
• Symmetrical peak shapes and excellent efficiency
• Stable between pH 2.5 and 7.5
• Available in 3 and 5μm particle sizes with an average pore diameter of 120Å

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Column Format

Analytical Column

Diameter (Metric)

4.6 mm

Flow Rate

0.5 to 3.0 mL/min

Length (Metric)

150 mm

Max. Pressure

5800 psi (400 bar)

Particle Size

5 μm

pH

2.5 to 7

Pore Size

120 Å

Surface Area

300 m²/g

Temperature

50°C

USP Type

L85

Stationary Phase

Hydrophobic Alkyl Chain with a Carboxyl Terminus

Product Line

Acclaim

Packing Material

Spherical, Fully Porous, Ultrapure Silica

Column Type

Mixed Mode

Endcapped

Proprietary

Phase

Reversed Phase, Ion Exchange, Ion Exclusion, HILIC

Limited warranty period: Subject to all warranty requirements and exclusions set out in our Terms and Conditions of Sale, this product is warranted from the date we ship the product and for ninety (90) days thereafter. Disclaimer to internal research use restriction: Any restrictions on the purchaser to utilize the product(s) for internal research purposes only does not apply to the product(s) on the web pages associated with this statement.