Thermo Scientific™ Acclaim™ Mixed Mode HILIC-1 HPLC Columns

Get all the advantages of reversed-phase and hydrophilic interaction liquid chromatography (HILIC) in one column with the Thermo Scientific™ Acclaim™ Mixed-Mode HILIC-1 column.

Get all the advantages of reversed-phase (RP) and hydrophilic interaction liquid chromatography (HILIC) in one column with the Thermo Scientific™ Acclaim™ Mixed-Mode HILIC-1 column. The high-efficiency, silica-based, mixed-mode stationary phase consists of a hydrophobic alkyl chain with a diol group at the terminus. The hydrophobic moiety supplies reversed-phase retention and the terminal diol group facilitates hydrophilic interactions. This unique combination provides adjustable selectivity with unsurpassed resolution and peak symmetry for a variety of both polar and nonpolar molecules.

Separates Both Polar and Nonpolar Molecules with Selectivity Complementary to RP Columns

• Operates in both RP and HILIC modes
• Retains highly polar molecules
• Covers broader application range than conventional diol-based columns, including nonionic ethoxylated surfactants, drug metabolites, lipids, and polyethylene glycols (PEGs)
• Stable between pH 2.5 and 7.5
• Available in 3 and 5μm particle sizes with an average pore diameter of 120Å

Column Format

Analytical Column

Diameter (Metric)

4.6 mm

Length (Metric)

150 mm

Max. Pressure

5800 psi (400 bar)

Particle Size

5 μm

pH

2.5 to 7.5

Pore Size

120 Å

Surface Area

300 m²/g

Temperature

50°C

USP Type

N/A

Stationary Phase

Hydrophobic Alkyl Chain with a Diol Group

Product Line

Acclaim

Packing Material

Spherical, Fully Porous, Ultrapure Silica

Column Type

Mixed Mode

Endcapped

Proprietary

Phase

Reversed Phase and HILIC

Limited warranty period: Subject to all warranty requirements and exclusions set out in our Terms and Conditions of Sale, this product is warranted from the date we ship the product and for ninety (90) days thereafter. Disclaimer to internal research use restriction: Any restrictions on the purchaser to utilize the product(s) for internal research purposes only does not apply to the product(s) on the web pages associated with this statement.