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A23187, free acid, Tocris Bioscience™

Catalog No. 123410
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Quantity:
10 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Calcium ionophore

Calcium ionophore that induces Ca2+-dependent cell death by increasing intracellular calcium concentration. Promotes intracelllular ROS generation and platelet particle formation (fragmentation) in vitro and in vivo. Can be used to induce autophagy in mammalian cells.

Chemical Identifiers

CAS 52665-69-7
Molecular Formula C29H37N3O6
Molecular Weight (g/mol) 523.63
MDL Number MFCD00151202,MFCD00151202
InChI Key HIYAVKIYRIFSCZ-CVXKHCKVSA-N
Synonym calcimycin, antibiotic a23187, ionophore a23187, calcium ionophore a23187, 4-benzoxazolecarboxylic acid, 5-methylamino-2-3,9,11-trimethyl-8-1-methyl-2-oxo-2-1h-pyrrol-2-yl ethyl-1,7-dioxaspiro 5.5 undec-2-yl methyl-, 6s-6alpha 2s*,3s* ,8beta r* ,9beta,11alpha, spectrum_001976, upcmld-dp093, upcmld-dp093:001, upcmld-dp093:002, upcmld-dp093:003
PubChem CID 97043288
IUPAC Name 5-(methylamino)-2-{[(2S,3S,8S,9R,11R)-3,9,11-trimethyl-8-[1-oxo-1-(1H-pyrrol-2-yl)propan-2-yl]-1,7-dioxaspiro[5.5]undecan-2-yl]methyl}-1,3-benzoxazole-4-carboxylic acid
SMILES CNC1=CC=C2OC(C[C@@H]3OC4(CC[C@@H]3C)O[C@H](C(C)C(=O)C3=CC=CN3)[C@H](C)C[C@H]4C)=NC2=C1C(O)=O

Specifications

Quantity 10 mg
Formula Weight 523.63
Percent Purity >98%
Chemical Name or Material A23187, free acid

Safety and Handling

Recommended Storage Desiccate at +4°C
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