9-Fluorenylmethyl chloroformate, 98+%, Thermo Scientific Chemicals

Description

Store cold

Base sensitive amino protecting group for solid-phase peptide synthesis9-Fluorenylmethyl chloroformate is used in capillary electrophoresis. It acts as a reagent in the precolumn derivatization of amines for HPLC and fluorescent detection. Further, it is used for derivatizing amino acids for HPLC analysis. In addition to this, it is used to prepare N-Fmoc amino acids for solid-phase peptide synthesis and oligonucleotide synthesis.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Base sensitive amino protecting group for solid-phase peptide synthesis9-Fluorenylmethyl chloroformate is used in capillary electrophoresis. It acts as a reagent in the precolumn derivatization of amines for HPLC and fluorescent detection. Further, it is used for derivatizing amino acids for HPLC analysis. In addition to this, it is used to prepare N-Fmoc amino acids for solid-phase peptide synthesis and oligonucleotide synthesis.

Solubility
Soluble in dioxane.

Notes
Moisture sensitive. Store in a cool place. Incompatible with alcohols and amines.

Specifications

Chemical Identifiers

• CAS: 28920-43-6
• Molecular Formula: C15H11ClO2
• Molecular Weight (g/mol): 258.701
• MDL Number: MFCD00001138
• InChI Key: IRXSLJNXXZKURP-UHFFFAOYSA-N
• Synonym: 9-fluorenylmethyl chloroformate, fmoc-cl, fmoc-chloride, fmoc chloride, 9h-fluoren-9-ylmethyl chloroformate, carbonochloridic acid, 9h-fluoren-9-ylmethyl ester, 9-fluorenylmethoxycarbonyl chloride, 9-fluorenylmethylchloroformate, 9h-fluoren-9-yl methyl carbonochloridate, 9h-fluoren-9-ylmethoxy carbonyl chloride
• PubChem CID: 34367
• IUPAC Name: 9H-fluoren-9-ylmethyl carbonochloridate
• SMILES: C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)Cl

• Melting Point: 60°C to 64°C
• Assay Percent Range: 98%
• Quantity: 25 g
• UN Number: UN2923
• Beilstein: 2279177
• Sensitivity: Moisture sensitive
• Solubility Information: Soluble in dioxane.
• Formula Weight: 258.7
• Percent Purity: 98%
• Chemical Name or Material: 9-Fluorenylmethyl chloroformate

Safety and Handling

Hazard Category	H302+H312+H332-H314-H335
Hazard Statement	GHS H Statement H314-H318-H302-H332 Causes severe skin burns and eye damage. Causes serious eye damage. Harmful if swallowed. Harmful if inhaled.
Precautionary Statement	P260-P264b-P270-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P501c
DOTInformation	Hazard Class: 6.1; Packaging Group: II
EINECSNumber	249-313-6
RTECSNumber	LQ6250000
TSCA	No
storageNote1	Moisture Sensitive
Recommended Storage	Keep cold; Store under Nitrogen

SDS

RUO – Research Use Only