6-Methylindole, 98%, Thermo Scientific Chemicals

Description

It is a reactant for preparation of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators, reactant for preparation of indole linked triazole derivatives as antifungal agents, reactant for preparation of N-β-D-xylosyl-indole derivatives as SGLT2 inhibitors for management of hyperglycemia in diabetes, reactant for preparation of aminoguanidine derivatives of arylsulfonylacylindoles as antifungal agents, reactant for preparation of indolylindazoles and indolylpyrazolopyridines as interleukin-2 inducible T cell kinase inhibitors, reactant for preparation of arylsulfonylacetylindoles as anti-HIV-1 agents. 6-Methylindole was used in the synthesis of benz[c,d]indol-3(1H)-one derivatives.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
It is a reactant for preparation of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators, reactant for preparation of indole linked triazole derivatives as antifungal agents, reactant for preparation of N-β-D-xylosyl-indole derivatives as SGLT2 inhibitors for management of hyperglycemia in diabetes, reactant for preparation of aminoguanidine derivatives of arylsulfonylacylindoles as antifungal agents, reactant for preparation of indolylindazoles and indolylpyrazolopyridines as interleukin-2 inducible T cell kinase inhibitors, reactant for preparation of arylsulfonylacetylindoles as anti-HIV-1 agents. 6-Methylindole was used in the synthesis of benz[c,d]indol-3(1H)-one derivatives.

Solubility
Insoluble in water.

Notes
Moisture and light sensitive. Store in dry condition. Keep away from active metals, bases, oxidizing agents and heat.

Specifications

Chemical Identifiers

• CAS: 3420-02-8
• MDL Number: MFCD00005682

• Melting Point: 29°C to 32°C
• Density: 1.059
• Boiling Point: 112°C (5 mmHg)
• Flash Point: >110°C (230°F)
• Molecular Formula: C11H15NO2
• Refractive Index: 1.6071
• Quantity: 250 mg
• Beilstein: 109708
• Sensitivity: Light sensitive
• Synonym: n-boc-aniline, tert-butyl phenylcarbamate, n-boc aniline, t-butyl carbanilate, tert-butyl carbanilate, carbanilic acid, tert-butyl ester, carbamic acid, phenyl-, 1,1-dimethylethyl ester, n-tert-butoxycarbonyl aniline, tert-butyl n-phenylurethane, carbanilic acid tert-butyl ester
• Solubility Information: Insoluble in water.
• InChI Key: KZZHPWMVEVZEFG-UHFFFAOYSA-N
• SMILES: CC(C)(C)OC(=O)NC1=CC=CC=C1
• IUPAC Name: tert-butyl N-phenylcarbamate
• Molecular Weight (g/mol): 193.25
• PubChem CID: 137930
• Formula Weight: 131.18
• Percent Purity: 98%
• Chemical Name or Material: 6-Methylindole

Safety and Handling

Hazard Category	H315-H319-H335
Precautionary Statement	P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
TSCA	No
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only