5 Lipoxygenase Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 100211IG150UL

Catalog No. 50-172-5975

Description

This gene encodes a protein which, with Arachidonate 5-lipoxygenase-activating protein, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation.

Specifications

• Antigen: 5 Lipoxygenase
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ALOX5
• Gene Alias: 5 Lipoxygenase, 5 LO, 5 LOX, 5LPG, ALOX5, LOG5
• Host Species: Rabbit
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunocytochemistry, Immunofluorescence, Western Blot
• Concentration: 0.53 mg/mL
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Accession No.: P09917, P48999
• Gene Symbols: ALOX5
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 11689, 240
• Content And Storage: -20°C
• Form: Liquid