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5-Iodo-2′-Deoxyuridine, MP Biomedicals™

Catalog No. MP21003572
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Quantity:
250 mg

Description

Active against vaccinia virus (orthopoxviruses). 5-Iodo-2′-Deoxyuridine, MP Biomedicals is a pyrimidine analog (halogenated thymidine) that compete with thymidine for incorporation into DNA of replicating cells. This incorporation results in radio sensiti

Chemical Identifiers

CAS 54-42-2
Molecular Formula C9H11IN2O5
Molecular Weight (g/mol) 354.10
MDL Number MFCD00134656
InChI Key XQFRJNBWHJMXHO-RRKCRQDMSA-N
Synonym idoxuridine, 5-iodo-2'-deoxyuridine, idoxuridin, 5-iododeoxyuridine, iododeoxyridine, iodoxuridine, iudr, joddeoxiuridin, idoxene, allergan 211
PubChem CID 5905
ChEBI CHEBI:147675
IUPAC Name 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidine-2,4-dione
SMILES OC[C@H]1O[C@H](C[C@@H]1O)N1C=C(I)C(=O)NC1=O

Specifications

Melting Point 196°C to 197°C (literature)
Density 2.148g/cm3 (Lit.)
Quantity 250 mg
Solubility Information Solubility at 25°C in mg/mL: 2.0 in water; 2.0 in 0.2N HCl; 74.0 in 0.2N NaOH; 4.4 in methanol; 2.6 in alc; 0.014 in ether; 0.003 in chloroform; 1.6 in acetone; 1.8 in ethyl acetate; 5.7 in dioxane.
Formula Weight 354.1
Percent Purity ∼99% by HPLC
Physical Form Powder

Safety and Handling

Recommended Storage Store at 0°C. Protect from light.
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