5-Fluorouridine, 97%, Thermo Scientific Chemicals

Description

5-Fluorouridine exhibits anticancer activity. It is often used in chemical and biochemical comparison studies with fluorouracil and thymine analogs. It is an active metabolite of Doxifluridine.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
5-Fluorouridine exhibits anticancer activity. It is often used in chemical and biochemical comparison studies with fluorouracil and thymine analogs. It is an active metabolite of Doxifluridine.

Solubility
Soluble in Methanol (Slightly), Water (Slightly).

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agents. Store at 4°C.

Specifications

Chemical Identifiers

• CAS: 316-46-1
• Molecular Formula: C9H11FN2O6
• Molecular Weight (g/mol): 262.193
• MDL Number: MFCD00036832
• InChI Key: FHIDNBAQOFJWCA-UAKXSSHOSA-N
• Synonym: 5-fluorouridine, 5-fur, uridine, 5-fluoro, furd, 5-fluoro-uridine, 5-fluorouracil 1beta-d-ribofuranoside, fluorouridine, chembl54918, 5-fluoro-1-beta-d-ribofuranosyl uracil, 1-2r,3r,4s,5r-3,4-dihydroxy-5-hydroxymethyl tetrahydrofuran-2-yl-5-fluoropyrimidine-2,4 1h,3h-dione
• PubChem CID: 9427
• ChEBI: CHEBI:40154
• IUPAC Name: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-fluoropyrimidine-2,4-dione
• SMILES: C1=C(C(=O)NC(=O)N1C2C(C(C(O2)CO)O)O)F

• Color: White
• Quantity: 5 g
• Beilstein: 33662
• Solubility Information: Soluble in Methanol (Slightly),Water (Slightly).
• Formula Weight: 262.19
• Percent Purity: 97%
• Physical Form: Powder
• Chemical Name or Material: 5-Fluorouridine

Safety and Handling

Hazard Category	Warning
Hazard Statement	GHS H Statement H341 Suspected of causing genetic defects.
Precautionary Statement	GHS P Statement P281-P201-P202-P308+P313-P405-P501a Use personal protective equipment as required. Obtain special instructions before use. Do not handle until all safety precautions have been read and understood. IF exposed or concerned: Get medical advice/attention. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.
EINECSNumber	206-260-3
RTECSNumber	YU8050000
TSCA	No
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only